Table of all transcripts that are detected in neurites in at least 3 out of the 20 studies included in our analysis. Listed are Ensembl gene names, short description (Biomart), number of datasets detecting a transcript with TPM > 10, average TPM value from all datasets and the number of studies reporting local translation of a transcript (Ouwenga et al., 2017; Ainsley et al., 2014; Zappulo et al., 2017; Shigeoka et al., 2016). Further columns not shown by default contain the TPM values from individual datasets and detection status of ribosome association in specific studies.
In addition to the main table there are subsetted tables that only contain the transcripts that where shown in the heatmap (Figure 2C) based on the top200 contributing genes to each PC. These show the mean TPM for datasets from primary neurons, mESC derived neurons and neuoblastoma cells lines instead of the average from all datasets.
Table of all transcripts that are significantly enriched in any of the analyzed datasets. Listed are Ensembl gene names, short description (Biomart), number of datasets reporting significant neurite enrichment, average of significant log2 neurite enrichment, number of datasets detecting a transcript with TPM > 10, indication if enrichment is exclusive to the high coverage studies using primary or non-primary neurons and rank of enriched transcript in extended online Table 1 (Ouwenga et al., 2017; Ainsley et al., 2014; Zappulo et al., 2017; Shigeoka et al., 2016). Additional columns not shown by default contain the log2 neurite/soma folc change values from individual datasets and detection status of ribosome association in specific studies.